Thousands of indigenous people of the region use Ayahuasca in sacred religious and healing ceremonies, as part of their traditional religions.
Ayahuasca is a sacred medicine used for millennia in order to enter the sacred supernatural world, to heal, divine, and worship.

The use of Ayahuasca and other plant teachers for visionary experiences as well as for healing purposes appears to be ancient. According to tradition, Banisteriopsis Caapi Vine, the main ingredient in most Ayahuasca brews, contains a sentient intelligence - with vast knowledge - which reveals guidance; the proper steps to follow in case of emotional or psychological problems, and even remedies that may be used for healing.